Cyclic vomiting syndrome and abdominal migraine Both cyclic vomiting syndrome and abdominal migraine are relatively unusual conditions that present with recurrent and severe paroxysmal vomiting or abdominal pain, separated by periods of weeks or months of good health. But while cyclic vomiting syndrome is characterized by recurrent, stereotypical episodes of intense nausea and vomiting lasting…
Read more
Adult CVS and confusion with Cannabinoid Hyperemesis Syndrome Adult CVS and confusion with Cannabinoid Hyperemesis Syndrome Coinciding with the increasing rates of cannabis abuse has been the recognition of a new clinical condition known as Cannabinoid Hyperemesis Syndrome. Cannabinoid Hyperemesis Syndrome is characterized by chronic cannabis use, cyclic episodes of nausea and vomiting, and frequent…
Read more
Adult CVS It has long been thought that CVS was a condition of childhood and adolescence. Now we know that adults also suffer from CVS. There is CVS that begins in childhood and may extend into adulthood as well as adult onset CVS. As so many adults can attest, the condition causes untold suffering and…
Read more
CVS Plus Cyclic vomiting syndrome is characterized by severe discrete episodes of nausea, vomiting, and lethargy. Approximately 25% of cases have coexisting neuromuscular disease manifestations (cyclic vomiting syndrome plus). To determine whether patients with cyclic vomiting syndrome and neuromuscular disease represent a distinct sub entity within cyclic vomiting syndrome, a clinical interview was conducted regarding…
Read more
Treatment of CVS Although limited data exist on treatment outcomes in children and adults with CVS, a NASPGHAN (North American Society for Pediatric Gastroenterology, Hepatology and Nutrition) consensus statement released in 2008 has outlined guidelines for management of CVS in children based mainly upon pediatric case series. A consensus statement for management of adults with…
Read more
CVS subgroups Subcategories of CVS have been identified, including CVS plus, catamenial CVS, and Sato’s variant of CVS. CVS plus is defined by the presence of at least two or more neuromuscular disease manifestations, including cognitive disorders, skeletal myopathy, cranial nerve dysfunction, and seizure disorders. Children with CVS plus are more likely to present at…
Read more
Cyclic Vomiting Syndrome and Mitochondrial Dysfunction and treatment Mitochondria are small organelles within the cell responsible for energy production and other critical functions. Mitochondrial diseases result from failures of the mitochondria, specialized compartments present in every cell of the body (except red blood cells). Mitochondria are responsible for creating more than 90% of…
Read more
Pathophysiology and Etiology Even though the etiology and pathophysiology of CVS are not known, studies have suggested several potential brain-gut mechanisms. Migraine CVS is considered to be a manifestation of migraine diathesis. The majority of children and adults have migraine diathesis as evidenced by the occurrence of migraine headaches in themselves and/or in their…
Read more
What is CVS? Cyclic vomiting syndrome, or cyclical vomiting syndrome, (CVS) is a chronic functional condition of unknown cause characterized by recurring attacks of intense nausea, vomiting, and sometimes abdominal pain, headaches, or migraines and prostration with no apparent cause. CVS typically develops during childhood but it may persist into adult life. Vomiting occurs at frequent intervals for hours or days. The…
Read more
With all of the heightened questions and concerns regarding COVID-19 from CVS patients and their caregivers from around the globe, CVSA USA/Canada consulted the World CVS expert, Dr. Venkatesan.